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  • Postdoctoral Research Scientist (m/f) – Microbial Genomics and Metagenomics

Postdoctoral Research Scientist (m/f) – Microbial Genomics and Metagenomics

TYPE DE CONTRAT : CDD - temps plein

is recruiting for a 1-year fixed term contract starting from 15th September 2019

 

a Postdoctoral Research Scientist (m/f) – Microbial Genomics and Metagenomics

 

About LNS

The “Laboratoire national de santé” (LNS) is a public institution operating under the supervision of the ministry of Health in Luxembourg. It is organized as a multidisciplinary institute which, along with an administrative department, includes six scientific departments related to the fields of morphological and molecular pathology, genetics, medical biology, microbiology, forensic medicine and health protection (www.lns.lu).

The LNS has new premises whose modern infrastructure is in line with the demands related to recent developments in medical and analytical science. The purpose of the LNS is to develop analytical and scientific expertise related to the prevention, diagnosis and monitoring of human diseases, to ensure the role of a national control or reference laboratory and to carry out medico-legal tasks.

The LNS contributes to the development, harmonization and promotion of laboratory methods in collaborative projects with other laboratories and develops research and teaching activities in association with ad hoc partners in Luxembourg and abroad.

About the mission

 

A postdoctoral researcher position is available at Laboratoire National de Santé to conduct metagenomics experiments as part of the “CampylOmic” research project funded by the FNR https://www.fnr.lu/projects/one-health-genomics-of-campylobacter-jejuni-in-luxembourg/.

The objective is to develop a culture-independent genotyping method to assess the population diversity of C. jejuni in environmental samples from metagenomic data.

The postdoc will be part of the Epidemiology and Microbial genomics team: https://lns.lu/departement/microbiologie/epidemiologie-genomique-microbienne/

 

Main activities

 

  • Develop a metagenomic protocol to assess the diversity in alleles of the 7 MLST housekeeping genes of Campylobacter jejuni in faecal material from animals or environmental samples
  • Test the method on pure culture and spiked samples
  • Optimize the DNA extraction of samples
  • Implement metagenomic analysis pipelines – develop and/or apply existing metagenomics bioinformatics tools
  • Develop a targeted sequencing approach to identify host species from the animal faecal sample (DNA barcoding approach)
  • Apply the optimized method on a collection of approximatively 300 samples

 

Desired profile

 

  • The candidate will have a PhD in microbiology, molecular biology, computational biology, bioinformatics, microbial genomics or related fields
  • Experience in high throughput genomic technologies including metagenomics
  • The candidate will be fluent in English, fluency in French is an asset
  • Knowledge in foodborne pathogens genotyping and culture of Campylobacter isolates are assets
  • Linux, Python or R programming skills
  • Knowledge of open source and commercial microbial NGS analysis pipelines (Seqsphere, Bionumerics, CGE Toolbox, Geneious)

 

We offer

 

  • A competitive salary, up to 55.000 € gross per year
  • An international and multidisciplinary environment

 

If you wish to apply, please send your application (CV, letter of intent and copies of your degrees) via our website :

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