bg image

Cholinergic innervation and ganglion cell distribution in Hirschsprung’s disease

  • accueil
  • Publications
  • Cholinergic innervation and ganglion cell distribution in Hirschsprung’s disease
Cholinergic innervation and ganglion cell distribution in Hirschsprung’s disease
2020 08-24

Authors: Braczynski AK, Gfroerer S, Beschorner R, Harter PN, Baumgarten P, Rolle U, Mittelbronn M

Abstract

Background:

The diagnostic gold standard of Hirschsprung’s disease (HD) is based on the histopathological assessment of colorectal biopsies. Although data on cholinergic innervation and ganglion cell (GC) distribution exist, only few studies have examined these two key features together. We assessed the pattern of cholinergic innervation and the amount of GCs in colorectal specimens of 14 HD patients.

BMC Pediatrics

Cholinergic innervation and ganglion cell distribution in Hirschsprung’s disease